Dr. Susheel Kumar Singh

Scientist Profile

Dr. Susheel Kumar Singh

Scientist - D

Date of Joining : 03/03/2024
Date of Joining(present post): 03/03/2024
Address(O):

ICMR-Regional Medical Research Centre, Chandrasekharpur,
Bhubaneswar-751023, Odisha

Address(R):

ICMR-Regional Medical Research Centre, Chandrasekharpur,
Bhubaneswar-751023, Odisha


Telephone no:

6370400680

Fax no:

Mobile No:

Email Id:

susheel.13@icmr.gov.in

Social Account:

Educational Qualifications:

Ph.D., M.Sc., B.Sc.


About Profile:

EDUCATION / TRAINING

 

INSTITUTION

DEGREE

YEAR

FIELD OF STUDY

APS University, Rewa, India

B.Sc.

1998-01

Zoology, Botany & Chemistry

APS University, Rewa, India

M.Sc.

2001-03

Biochemistry

RD University, Jabalpur, India

Ph.D.

2003-07

Biochemistry

Post-doctoral training:

 

 

 

University of Copenhagen, Denmark

-

2011-17

Malaria Molecular biology

IIIM, Jammu, India

-

2010-11

Malaria Molecular biology

                         

POSITIONS / JOBS

2024-Till date 

2021- 2024

2017- 2021

Scientist -D, ICMR-RMRC, Bhubaneswar, India

DHR-ICMR, NRI/PIO fellow, ICMR-RMRC, Bhubaneswar, India

Assistant Professor, CMP-University of Copenhagen, Denmark

2008-2010

Scientst-1, R & D Division, Gennova Biopharmaceuticals, Pune, India

GRANTS / FUNDINGS

Research grants (Ongoing):

  1.  ICMR, India (Intramural fund)    Dr. Sanghamitra Pati (PI) and Susheel Singh (Co-PI)           2022 – 2027

    Project title:  Establishing efficient recombinant protein expression platforms for developing effective diagnostics and vaccines                                                                                                                  (Total Budget Rs. 10.0 million)

  2. DBT-BIRAC-NBM, India        Susheel Singh (Lead PI) and Multi-centric (Co-PI)                    2021 – 2024

    Project title:  Multi-stage malaria vaccine candidates for the prevention of Plasmodium falciparum infection in mosquito and pre-erythrocytic development in man                                                      (Total Budget Rs. 77.6 million)

  3. DHR-ICMR, India                 Susheel Singh (PI) and Dr. Sanghamitra Pati (mentor)               2021 – 2024                              

    Project title: Designing a versatile Virus-Like Particle (VLP) platform amenable to efficient protein conjugation for improving immunogenicity against antigens from Malaria and Japanese Encephalitis (Total Budget Rs.8.9 million)

Research grants (Completed):

  1. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)                     2018 - 2019

    Project title:   LCS of Pfs230-6C Chimeric Antigens and Pfs48/45 nanoparticle fusion: Feasibility study in L. lactis

                                                                                                                                         (Total Budget $253418)

  2. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)                     2019

    Project title:   Pfs48/45 G397L Stabilization Mutant Expression in Lactococcus lactis         (Total Budget $63938)

  3. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)                   2018 - 2019

    Project title: To produce 500mg cGMP compline rCSP for non-clinical use.                  (Total Budget  $204629)   

  4. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)                     2018 - 2019

    Project title: To develop Ni++ independent purification of R0.6C to technology transfer to dedicated GMP manufacture.                                                                                                                       (Total Budget $318193)       

  5. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)               2018 - 2019

    Project title: Construct development and pilot production of a Glideosome-associated protein 40 (GAP40) in gram-positive bacteria and yeast.                                                                                            (Total Budget $230310)                 

  6. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)               2018 - 2019

    Project title: Development of P. falciparum UIS3 constructs in L. lactis.                             (Total Budget $120483)           

  7. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)               2017 - 2018

    Project title: Development of P. falciparum rPfCSP for non-clinical use L. lactis.                     (Total Budget $76306)   

  8. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)              2016 - 2018

    Project title: Process development and formulation studies of R0.6C                                 (Total Budget $632746)   

  9. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)               2016 - 2018      Project title: Production of 50mg of immune purified R0.6C                                                (Total Budget $111647)
  10. PATH-MVI, USA            Prof. Michael Theisen (PI) and  Susheel Singh (Co-PI)               2015 - 2016Project title: GMZ2’.10C chimeric vaccine targeting transmission stages of P. falciparum.   (Total Budget $525674)                                                                                    

                              

 

EXPERTISE / COMPETENCE

Recombinant protein expression & purification (different platforms bacteria, yeast and insect cell lines), vaccine and diagnostic kits development. Production of different Virus-Like Particles (VLP) platforms: AP205 and Hepatitis B (HBsAg: surface antigen VLP & HBcAg: core antigen derived VLP) as a vaccine delivery system.

Profiling of immunological responses (cellular and humoral); Immune-epidemiology. Ability to write competitive grants and lead multi-institutional research projects. 

Intellectual Property Rights:

  1. Singh SK and Theisen M, publication no. US/2022/0194996A1 entitled “Multivalent malaria transmission-blocking vaccines” (2022 June 23)
  2. PATH, Sumitomo Dainippon Pharma Co., Ltd., Theisen, M and Singh, SK “PRE-ERYTHROCYTIC MALARIA VACCINES” US20230241194A1 (2023 Aug 03)

Book Chapters:

  1. Susheel K. Singh* and Vandana Singh “Method for Production of Cysteine-Rich Proteins in Lactococcus lactis Expression System” Insoluble Proteins. Methods in Molecular Biology. (2022 Jan 01) (MIMB, volume 2406), ISSN No. 1064-3745. (*Corresponding Author)
  2. Susheel K Singh*, Mohammad Naghizadeh, Jordan Plieskatt, Subhash Singh, Michael Theisen “Cloning and Recombinant Protein Expression in Lactococcus lactisAdvanced Methods in Structural Biology. Methods in Molecular Biology. (2023 April 25) (MIMB, volume 2652). ISSN No.1064-3745 (*Corresponding Author)
  3. Mohammad Naghizadeh, Susheel K Singh, Jordan Plieskatt, Ebenezer Addo Ofori, Michael Theisen “Production and Purification of Plasmodium Circumsporozoite Protein in Lactococcus lactisRecombinant Glycoproteins: Methods and Protocols. (2024 Feb 06) Methods in Molecular Biology (MIMB, volume 2762). ISSN No.1064-3745

 

Publications (reverse chronological order): 

  1. Jordan Plieskatt, Peter Bang, Grith Krøyer Wood, Mohammad Naghizadeh, Susheel K. Singh, Matthijs M. Jore, Michael Theisen “Clinical formulation development of Plasmodium falciparum malaria vaccine candidates based on Pfs48/45, Pfs230, and PfCSP” Vaccine (2024 Feb 14); 42, 1980-1992. ISSN No.: 0264-410X IF-4.169
  2. B Alfred Tiono, Jordan L Plieskatt, Alphonse Ouedraogo, Ben Idriss Soulama, Kazutoyo Miura, Edith C Bougouma, Mohammad Naghizadeh, Aissata Barry, Jean Baptiste B Yaro, Sem Ezinmegnon, Noelie B Henry, Ebenezer Ofori, Bright Adu, Susheel K Singh, Augustin Konkobo, Karin Lövgren Bengtsson, Amidou Diarra, Cecilia Carnrot, Jenny M Reimer, Amidou Z Ouedraogo, Moussa Tienta, Carole A Long, Issa N Nebie, Issaka Sagara, Sodiomon B Sirima, Michael Theisen “A randomized first-in-human Phase 1 trial of differentially adjuvanted Pfs48/45 malaria vaccines in Burkinabé adults” The Journal of Clinical Investigation (2024 Jan 30); ISSN No.: 1558-8238 IF-15.9
  3. Isabel Byrne, Timothy William, Tock H. Chua, Catriona Patterson, Tom Hall, Mark Tan, Chetan Chitnis, John Adams, Susheel K. Singh, Lynn Grignard, Kevin K. A. Tetteh, Kimberly M. Fornace & Chris J. Drakeley “Serological evaluation of risk factors for exposure to malaria in a pre‑elimination setting in Malaysian Borneo” Scientific Reports (2023 Aug 10); 13, 12998. ISSN No.: 2045-2322 IF-4.997
  4. Eric Kyei-Baafour, Kwadwo Asamoah Kusi, Fareed KN Arthur, Regis W Tiendrebeogo, Eunice Owusu-Yeboa, Susheel K Singh, Sarah Friedrich, Thomas A Gerds, Daniel Dodoo, Michael Theisen, Bright Adu “High opsonic phagocytosis activity and growth inhibition of merozoites are associated with RON4 antibody levels and protect against febrile malaria in Ghanaian childrenFrontiers in Immunology (2023 May 01); 14, 1161301. ISSN No.: 1664-3224 IF-8.786
  5. Barbara de Oliveira Baptista, Ana Beatriz Lopes de Souza, Luana Santos de Oliveira, Hugo Amorim dos Santos de Souza, Jenifer Peixoto de Barros, Lucas Tavares de Queiroz, Rodrigo Medeiros de Souza, Linda Eva Amoah, Susheel K. Singh, Michael Theisen, Rodrigo Nunes Rodrigues-da-Silva, Evelyn Kety Pratt Riccio, Paulo Renato Rivas Totino, Josué da Costa Lima-Junior, Cláudio Tadeu Daniel-Ribeiro and Lilian Rose Pratt-Riccio “B-Cell Epitope Mapping of the Plasmodium falciparum Malaria Vaccine Candidate GMZ2.6c in a Naturally Exposed Population of the Brazilian AmazonVaccines (2023 Feb 15); 11, 446. ISSN No.: 2076-393X IF-7.8
  6. Sarbani Mishra, Madhusmita Rout, Sunita Panda, Susheel K. Singh, Rohan Sinha, Budheswar Dehury, and Sanghamitra Pati “An immunoinformatic approach towards development of a potent and effective multi-epitope vaccine against monkeypox virus (MPXV)Journal of Biomolecular Structure and Dynamics (2023 Jan 2);1-14., ISSN No.: 0739-1102 IF-4.152
  7. Kapil Vashisht, Sukrit Srivastava, Vandana, Ram Das, Supriya Sharma, Nitin Bhardwaj, Anup kumar Anvikar, Susheel K. Singh, Tong-Soo Kim, Byoung-Kuk Na, Ho-Joon Shin, Kailash C Pandey “Cyclic constrained immunoreactive peptides from crucial P. falciparum proteins: potential implications in malaria diagnosticsTranslational Research (2022 Nov 10) 249:28-36, ISSN No.: 1931-5244 IF-10.117
  8. Roos M. de Jong, Susheel K. Singh,  Karina Teelen, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Will J. R. Stone, Emily Locke, Jordan Plieskatt, Michael Theisen, Teun Bousema, and Matthijs M. Jore “Heterologous expression and pre-clinical evaluation of novel Plasmodium falciparum transmission blocking vaccine candidatesFrontier in Immunology, ( 2022 June 23); 13: 909060, ISSN No.: 1664-3224  IF-8.786
  9. Sylvester Dassah, Bright Adu, Régis W. Tiendrebeogo, Susheel K. Singh, Fareed K. N. Arthur, Sodiomon B. Sirima, and Michael Theisen “GMZ2 Vaccine-Induced Antibody Responses, Naturally Acquired Immunity and the Incidence of Malaria in Burkinabe ChildrenFrontier in Immunology, ( 2022 June 02); 13: 899223, ISSN No.: 1664-3224  IF-8.786
  10. Afshana Quadiri, Lokesh Kori, Susheel K. Singh, Anupkumar R. Anvikar “Antibody Responses Against Plasmodium falciparum MSP3Protein During Natural Malaria Infection in Individuals Living in Malaria-Endemic Regions of India Natl. Acad. Sci., India (2022 April 06); 1-7 ISSN No.: 2250-1746 IF-0.96
  11. Barbara Oliveira Baptista, Ana Beatriz Lopes de Souza, Evelyn Kety Pratt Riccio, Cesare Bianco-Junior, Paulo Renato Rivas Totino, João Hermínio Martins da Silva, Michael Theisen, Susheel K. Singh, Linda Eva Amoah, Marcelo Ribeiro-Alves, Rodrigo Medeiros Souza, Josué Costa Lima-Junior, Cláudio Tadeu Daniel-Ribeiro & Lilian Rose Pratt-Riccio “Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in individuals living in Brazilian malaria-endemic areasMalaria Journal (2022 Jan 10) 21:6 ISSN No.: 1475-2875 IF-3.469
  12. Susheel K. Singh, Jordan Plieskatt, Bishwanath K. Chourasia, Vandana Singh, Karin Lövgren Bengtsson, Jenny M Reimer, Renate C. van Daalen , Karina Teelen , Marga van de Vegte-Bolmer , Geert-Jan van Gemert Matthijs M. Jore, Michael Theisen “Preclinical development of a Pfs230-Pfs48/45 chimeric malariatransmission-blocking vaccine” npj Vaccines (2021 Oct 8) 6:120 ISSN No.: 2059-0105 IF- 9.399
  13. Michael Alifrangis, Tine Kliim Nydahl, Samuel Yao Ahorhorlu, Magatte Ndiaye, Manoj Kumar Das, Helle Hansson, Marina Crespo Bravo, Christian William Wang, John Lusingu, Michael Theisen, Susheel K. Singh, Subhash Singh, Susana Campino, Ole Lund, Cally Roper “Identification of Single-Nucleotide Polymorphisms in the Mitochondrial Genome and Kelch 13 Gene of Plasmodium falciparum in Different Geographical PopulationsAm J Trop Med Hyg (2021 July 16) 21-0320 ISSN No.:1476-1645  IF- 345
  14. Eric Kyei-Baafour, Mavis Oppong, Kwadwo Asamoah Kusi, Abena Fremaah Frempong, Belinda Aculley, Fareed K. N. Arthur, Regis Wendpayangde Tiendrebeogo, Susheel K. Singh, Michael Theisen, Margaret Kweku, Bright Adu, Lars Hviid, Michael Fokuo Ofori “Suitability of IgG responses to multiple Plasmodium falciparum antigens as markers of transmission intensity and pattern” PLoS ONE (2021 April 2021) 16(4): e0249936 ISSN No.:1932-6203 IF-3.752
  15. Cyrielle Fougeroux, Louise Goksøyr, Manja Idorn, Vladislav Soroka, Sebenzile K. Myeni, Robert Dagil, Christoph M. Janitzek, Max Søgaard, Kara-Lee Aves, Emma W. Horsted, Sayit Mahmut Erdoğan, Tobias Gustavsson, Jerzy Dorosz, Stine Clemmensen, Laurits Fredsgaard, Susan Thrane, Elena E. Vidal-Calvo, Paul Khalifé, Thomas M. Hulen, Swati Choudhary, Michael Theisen, Susheel K Singh, Asier Garcia Senosiain, Linda Van Oosten, Gorben Pijlman, Bettina Hierzberger, Tanja Domeyer, Blanka W. Nalewajek, Anette Strøbæk, Magdalena Skrzypczak, Laura F. Andersson, Tim J. Dalebout, Kasper Iversen, Lene H. Harritshøj, Benjamin Mordmüller, Henrik Ullum, Line S. Reinert, Willem Adriaan de Jongh, Marjolein Kikkert, Søren R. Paludan, Thor G. Theander, Morten A. Nielsen, Ali Salanti, Adam F. Sander “Capsid-like particles decorated with the SARS2-CoV-2 receptor-binding domain elicit strong virus neutralization activity” Nature Communications, (2021 Jan 23) 12:324; ISSN No.: 2041-1723 IF- 69
  16. Susheel K. Singh, Jordan Plieskatt, Bishwanath K. Chourasia, Amanda Fabra García, Asier Garcia-Senosiain, Vandana Singh, Karin Lövgren Bengtsson, Jenny M Reimer, Robert Sauerwein, Matthijs M. Jore, Michael Theisen “A reproducible and scalable process for manufacturing a Pfs48/45 based Plasmodium falciparum transmission-blocking vaccine” Frontier in Immunology, ( 2021 Jan 11); 11:606266 ISSN No.: 1664-3224 IF-8.786
  17. Lindsey Wu, Julia Mwesigwa, Muna Affara, Mamadou Bah, Simon Correa, Tom Hall, Susheel K Singh, James G Beeson, Kevin KA Tetteh, Immo Kleinschmidt, Umberto D'Alessandro, Chris Drakeley. “Sero-epidemiological evaluation of malaria transmission in The Gambia before and after mass drug administration” BMC Medicine, (2020 Nov 13); 18(1):331. ISSN No.: 1741-7015 IF-11.806
  18. Lindsey Wu, Julia Mwesigwa, Muna Affara, Mamadou Bah, Simon Correa, Tom Hall, Susheel K Singh, James G. Beeson, Kevin K. A. Tetteh, Immo Kleinschmidt, Umberto D’Alessandro and Chris Drakeley. “Antibody responses to a suite of novel serological markers for malaria surveillance demonstrate strong correlation with clinical and parasitological infection across seasons and transmission settings in The Gambia” BMC Medicine, (2020 Sep 25); 18(1):304. ISSN No.: 1741-7015  IF-11.806
  19. Lotus L. van den Hoogen, Paolo Bareng, Joana Alves, Ralph Reyes, Malou Macalinao, Júlio M. Rodrigues, José M. Fernandes, Lara F. Goméz, Tom Hall, Susheel K. Singh, Kimberly Fornace, Jennifer Luchavez, Alan Kitchen, Peter Chiodini, Fe Espino, Kevin K. A. Tetteh, Gillian Stresman, Nuno Sepúlveda and Chris Drakeley. “Comparison of Commercial ELISA Kits to Confirm the Absence of Transmission in Malaria Elimination Settings” Frontiers in Public Health, (2020 Sep 09); 8:480. ISSN No.: 2296-2565 IF-6.461
  20. Lotus L. van den Hoogen, Gillian Stresman, Jacquelin Présumé, Ithamare Romilus, Gina Mondélus, Tamara Elismé, Alexandre Existe, Karen E. S. Hamre, Ruth A. Ashton, Thomas Druetz, Vena Joseph, James G. Beeson, Susheel K. Singh, Jacques Boncy, Thomas P. Eisele, Michelle A. Chang, Jean F. Lemoine, Kevin K. A. Tetteh, Eric Rogier and Chris Drakeley. “Selection of Antibody Responses Associated with Plasmodium falciparum Infections in the Context of Malaria Elimination” Frontier in Immunology, (2020 May 15); 11:928. ISSN No.: 1664-3224 IF-8.786
  21. Asier Garcia-Senosiain, Ikhlaq Hussain Kana, Susheel K Singh, Bishwanath Kumar Chourasia, Manoj Kumar Das, Danial Dodoo, Subhash Singh, Subhash Singh, Michael Theisen. “Peripheral Merozoite Surface Proteins Are Targets of Naturally Acquired Immunity against Malaria in both India and GhanaInfection and Immunity, (2020 Mar 23); 88(4). e00778-19. ISSN No.: 1083-351X IF- 3.441
  22. Bishwanath Kumar Chourasia, Arunaditya Deshmukh, Inderjeet Kaur, Gourab Paul, Ashutosh Panda, Sumit Rathore, Susheel K. Singh, Michael Theisen, Asif Mohmmed, Pawan Malhotra “Plasmodium falciparum Clag9 associated PfRhopH complex is involved in merozoite binding to human erythrocytesInfection and Immunity, (2020 Jan 22); 88(2): e00504-19. ISSN No.: 1098-5522 IF- 3.441
  23. Susheel K. Singh, Jordan Plieskatt, Bishwanath Kumar Chourasia, Vandana Singh, Judith M. Bolscher, Koen J. Dechering, Bright Adu, Blanca López-Méndez, Swarnendu Kaviraj, Emily Locke, C. Richter King, Michael Theisen “The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is a pure and stableJournal of Biological Chemistry, (2020 Jan 10); 295(2):403-414. ISSN No.: 1083-351X IF-5.486
  24. Harvinder K Khera, Susheel K Singh, Subhash Singh “Chorismate synthase from malaria parasites is bifunctional enzymeMolecular and Biochemical Parasitology, (2019 Aug 2); 233:111202 ISSN No.: 0166-6851 IF-1.759
  25. Ikhlaq Hussain Kana, Susheel K Singh, Asier Garcia-Senosiain, Danial Dodoo, Subhash Singh, Bright Adu, and Michael Theisen “Breadth of functional antibodies is associated with Plasmodium falciparum merozoite phagocytosis and protection against febrile malariaJournal of Infectious Diseases, (2019 June 19); 220(2):275-284, ISSN No.: 1537-6613 IF-7.759
  26. Susheel K Singh, Susan Thrane, Bishwanath K. Chourasia, Karina Teelen, Wouter Graumans, Rianne Stoter, Geert-Jan van Gemert, Marga G. van de Vegte-Bolmer, Morten A. Nielsen, Ali Salanti, Adam F. Sander, Robert W. Sauerwein, Matthijs M. Jore and Michael Theisen “Pfs230 and Pfs48/45 fusion proteins elicit strong transmission-blocking antibody responses against Plasmodium falciparumFrontier in Immunology. (2019 June 5) 10:1256. ISSN No.: 1664-3224 IF-8.786
  27. Lindsey Wu, Tom Hall, Isaac Ssewanyana, Tate Oulton, Catriona Patterson, Hristina Vasileva, Susheel K Singh, Muna Affara, Julia Mwesigwa, Simon Correa, Mamadou Bah, Umberto D'Alessandro Nuno Sepúlveda, Chris Drakeley and Kevin K A Tetteh “Optimisation and standardisation of a multiplex immunoassay of diverse Plasmodium falciparum antigens to assess changes in malaria transmission using seroepidemiologyWellcome Open Research, (2019 April 23): 4:26. ISSN No.: 2398-502X IF-4.00
  28. Lotus L. van den Hoogen, Jona Walk, Tate Oulton, Isaie J. Reuling, Linda Reiling, James Beeson, Ross L. Coppel, Susheel K Singh, Simon J. Draper, Robert Sauerwein, Chris Drakeley, Teun Bousema and Kevin K. Tetteh “Antibody responses to markers of recent exposure are associated with cumulative parasite biomass in low-density infectionsFrontiers in Microbiology, (2019 Jan16); 9:330, ISSN No.: 1664-302X IF-6.064
  29. Ikhlaq Hussain Kana, Asier Garcia-Senosiain, Susheel K Singh, Régis W Tiendrebeogo, Bishwanath Kumar Chourasia, Pawan Malhotra, Surya K. Sharma, Manoj K. Das, Subhash Singh, Bright Adu, and Michael Theisen “Cytophilic antibodies against key Plasmodium falciparum blood stage antigens contribute to protection against clinical malaria in a high transmission region of Eastern IndiaJournal of Infectious Diseases, (2018 Aug 14); 218(6):956-965, ISSN No.: 1537-6613 IF-7.759
  30. Arunaditya Deshmukh, Bishwanath Kumar Chourasia, Sonali Mehrotra, Ikhlaq Hussain Kana, Gourab Paul, Ashutosh Panda, Inderjeet Kaur, Susheel K Singh, Sumit Rathore, Aparup Das, Priya Gupta, Kalamuddin Md, SK Ghakar, Asif Mohmmed, Michael Theisen and Pawan Malhotra “Plasmodium falciparum MSP3 exists in a complex on the merozoite surface and generates antibody response during natural infectionInfection and Immunity, (2018 July 23); 86(8), e00067-18. ISSN No.: 1098-5522 IF-441
  31. Susheel K Singh, Régis W. Tiendrebeogo, Bishwanath Kumar Chourasia, Ikhlaq Hussain Kana, Subhash Singh and Michael Theisen “Lactococcus lactis provides an efficient platform for the production of disulfide-rich recombinant proteins from Plasmodium falciparum” Microbial Cell Factories, (2018 April 5); 17(1): 55, ISSN No.: 1475-2859 IF-6.352
  32. Gourab Paul, Arunaditya Deshmukh, Bishwanath Kumar Chourasia, Md  Kalamuddin, Ashutosh Panda, Susheel K Singh, Puneet K Gupta, Asif Mohmmed, Virander S Chauhan, Michael Theisen, Pawan Malhotra “Protein-protein interaction studies reveal the Plasmodium falciparum  Merozoite surface protein-1 region involved in complex formation that binds to human erythrocytesBiochemical Journal, (2018 March 29); 475(6):1197-1209, ISSN No.: 1470-8728 IF-4.097
  33. Will JR Stone, Joseph J Campo, André Lin Ouédraogo, Lisette Meerstein-Kessel, Isabelle Morlais, Dari Da, Anna Cohuet, Sandrine Nsango, Colin J Sutherland, Marga van de Vegte-Bolmer, RianneSiebelink-Stoter, Geert-Jan van, Gemert, Wouter Graumans, Kjerstin Lanke, Adam D Shandling, Jozelyn V Pablo, Andy A Teng, Sophie Jones, Roos M de Jong, Amanda Fabra-García, John Bradley, Will Roeffen, Edwin Lasonder, Giuliana Gremo, Evelin Schwarzer , Chris J Janse, Susheel K Singh, Michael Theisen, Phil Felgner, Matthias Marti, Chris Drakeley, Robert Sauerwein, Teun Bousema and Matthijs M. Jore “Unravelling the immune signature of Plasmodium falciparum transmission reducing immunityNature Communications, (2018 Feb 8); 9(1):558, ISSN No.: 2041-1723 IF- 69
  34. Linda E Amoah, Festus K Acquah, Ruth Ayanful-Torgby, AkuaOppong, Joana Abankwa, Evans K Obboh, Susheel K Singh and Michael Theisen “Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern GhanaParasites & Vectors, (2018 Jan 5); 11(1):13, ISSN No.: 1756-3305 IF-4.047
  35. Ulrik H Mistarz, Susheel K Singh, Tam TTN Nguyen, Will Roeffen, Fen Yang, Søren Madsen, Astrid Vrang, Régis Wendpayangde Tiendrebeogo, Ikhlaq Hussain Kana, Robert W Sauerwein, Michael Theisen, Kasper D Rand “Expression, purification and characterization of GMZ2’.10C, a complex disulphide-bonded fusion protein vaccine candidate against the asexual and sexual life-stages of the malaria-causing Plasmodium falciparum parasitePharmaceutical Research, (2017 Sep); 34(9):1970-1983, ISSN No.: 1573-904X Equal contribution IF-4.914
  36. LE Amoah, SV Nuvor, EK Obboh, FK Acquah, K Asare, Susheel K Singh, JN Boampong, M Theisen and KC Williamson “Natural antibody responses to Plasmodium falciparum MSP3 and GLURP(R0) antigens are associated with low parasite densities in malaria patients living in the Central Region of GhanaParasites & Vectors, (2017 Aug 23); 10:395, ISSN No.: 1756-3305 IF-4.047
  37. Festus K Acquah, Evans K Obboh, Kwame Asare, Johnson N Boampong, Samuel Victor Nuvor, Susheel K Singh, Michael Theisen, Kim C Williamson and Linda Eva Amoah “Antibody responses to two new Lactococcus lactis produced recombinant Pfs48/45 and Pfs230 proteins increase with age in malaria patients living in the Central Region of GhanaMalaria Journal, (2017 Aug 1); 16(1):306, ISSN No.: 1475-2875 IF-3.469
  38. Susheel K Singh, Susan Thrane, Christoph M Janitzek, Morten A Nielsen, Thor G Theander, Robert W Sauerwein, Michael Theisen, Ali Salanti, Adam F Sander “Improving the malaria transmission-blocking activity of a Plasmodium falciparum 48/45 based vaccine antigen by SpyTag/SpyCatcher mediated virus-like displayVaccine, (2017 June 27); 35(30):3726-3732, ISSN No.: 0264-410X IF-4.169
  39. Susheel K Singh, Will Roeffen, Ulrik H Mistarz, Bishwanath Kumar Chourasia, Fen Yang, Kasper D Rand, Robert Sauerwein and Michael Theisen “Construct design, fermentation, and purification of Plasmodium falciparum 48/45 R0.6C subunit protein produced in Lactococcus lactis as candidate vaccine” Microbial Cell Factories, (2017 May 31); 16(1):97, ISSN No.: 1475-2859 IF-6.352
  40. Harvinder K Khera, Susheel K Singh, Subhash Singh. “Heterologous expression of Chorismate synthase from Plasmodium falciparum in Escherchia coli: Optimization of conditions for obtaining soluble and stable recombinant protein” Australian Journal of Basic and Applied Sciences, (2017 May 18); 11(8): 12-19, ISSN No.: 2309-8414 IP-2.5
  41. Ikhlaq H Kana, Bright Adu, Régis W Tiendrebeogo, Susheel K Singh, Daniel Dodoo, and Michael Theisen “Naturally acquired antibodies target the Glutamate-Rich Protein (GLURP) on intact merozoites and predict protection against febrile malaria in Ghanaian childrenJournal of Infectious Diseases, (2017 Feb 15); 215(4):623-630, ISSN No.: 1537-6613 IF-7.759
  42. Gourab Paul, Arunaditya Deshmukh, Inderjeet Kaur, Sumit Rathore, Surbhi Dabral, Ashutosh Panda, Susheel K Singh, Asif Mohmmed, Michael Theisen and Pawan Malhotra “A novel Pfs38 protein complex on the surface of Plasmodium falciparum blood-stage merozoitesMalaria Journal, (2017 Feb 16); 16(1):79, ISSN No.: 1475-2875 IF-3.469
  43. HK Khera, Susheel K Singh, R Mir, V Bhardwaj, S Singh “A HR-MS Based Method for the Determination of Chorismate synthase Activity Protein and peptide letters, (2017 Jan); 24(3):229-234, ISSN No.: 1875-5305 IF-1.890
  44. Harvinder Kour Khera, Susheel K Singh, GN Bhat, Subhash Singh “Conserved cysteines in malaria Chorismate Synthase indicate their important role in protein structure and functionIndian Journal of Biochemistry and Biophysics, (2016 Oct); 53:161-168, ISSN No.: 0975-0959 IF-1.476
  45. Susan L Baldwin, Will Roeffen, Susheel K Singh, Regis W Tiendrebeogo, Michael Christiansen, Elyse Beebe, Darrick Carter, Christopher B Fox, Randall F Howard, Steven G Reed, Robert Sauerwein, and Michael Theisen “A synthetic TLR4 agonist enhances bifunctional antibodies and polyfunctional CD4+T cell response against a Plasmodium falciparum multistage protein vaccine” Vaccine, (2016 April 27); 34(19): 2207-2215, ISSN No.: 0264-410X IF-4.169
  46. Regis W Tiendrebeogo, Bright Adu, Susheel K Singh, Morten H Dziegiel, IssaNébié, Sodiomon B Sirima, Michael Christiansen, Daniel Dodoo, Michael Theisen “Antibody-dependent cellular inhibition is associated with protection against febrile malaria in a longitudinal cohort study involving Ghanaian children” Open forum Infectious diseases, (2015 April 10) 2(2):ofv044, ISSN No.: 2328-8957 IF-3.835
  47. Susheel K Singh, Will Roeffen, Gorm Andersen, TeunBousema, Michael Christiansen, Robert Sauerwein and Michael Theisen “A Plasmodium falciparum 48/45 single epitope R0.6Csubunit protein elicits high levels of transmission blocking antibodies” Vaccine, (2015 April 15); 33(16):1981-6, ISSN No.: 0264-410X IF-4.169
  48. Regis W Tiendrebeogo, Bright Adu, Susheel K Singh, Daniel Dodoo, Morten H Dziegiel, Benjamin Mordmüller, Issa O Nebie, Sodiomon B Sirima, Michael Christiansen, Michael Theisen “High-throughput tri-color flow cytometry technique to assess Plasmodium falciparum parasitemia in bioassays” Malaria Journal, (2014 Oct 20); 13:412, ISSN No.: 1475-2875 IF-3.469
  49. Michael Theisen, Will Roeffen, Susheel K Singh, Gorm Anderson, Linda Amogh, Marga van de Vegte-Bolmer, Theo Arens, Régis Wendpayangde Tiendrebeogo, Sophie Jones, Teun Bousema, Bright Adu, Morten H Dziegiel, Michael Christiansen, and Robert Sauerwein; “A multi-stage malaria vaccine candidate targeting both transmission and asexual parasite life-cycle stages” Vaccine, (2014 May 7); 32(22):2623-30, ISSN No.: 0264-410X IF-4.169
  50. Sharma Anjana, Susheel K Singh, Kori Lokesh, Bora Chandan R. and Shukla Varsha “Evaluation of water quality of river Narmada and its correlation with the occurrence of enteropathogensJournal of Environmental Science and Engineering, (2014 Jan); 56(1): 45-52, ISSN No.: 0367-827X. IF-0.70
  51. Micha P Jepsen, Prajakta S Jogdand, Susheel K Singh, Meral Esen, Michael Christiansen, Saadou Issifou, Aurore B Hounkpatin, UlysseAteba-Ngoa, Peter G Kremsner, Morten H Dziegiel, Severin Olesen-Larsen, Søren Jepsen, Benjamin Mordmüller and Michael Theisen “The malaria vaccine candidate GMZ2 elicits high-level functional antibodies in individuals from malaria-endemic and non-endemic areas” Journal of Infectious Diseases, (2013 Aug 1); 208(3):479-88, ISSN No.: 1537-6613 IF-7.759
  52. Prajakta S Jogdand,Susheel K SinghMichael ChristiansenMorten H DziegielSubhash Singh and Michael Theisen “Flow cytometric readout based on Mitotracker Red CMXRos staining of live asexual blood stage malarial parasites reliably assesses antibody dependent cellular inhibition” Malaria Journal, (2012 July 20); 11:235, ISSN No.: 1475-2875 Equal contribution IF-3.469
  53. Anjana Sharma, Susheel K Singh and Divya Bajpai “Phenotypic and Genotypic characterization of Shigella spp with reference to its virulence genes and Antibiogram analysis from river Narmada” Microbiological Research, (2010); 165(1):33-42, ISSN No.: 0944-5013 IF-5.19
  54. Anjana Sharma, Susheel K Singh and Lokesh Kori “Molecular epidemiological characteristics of Shigella spp isolated from river Narmada during the period 2005-2006” Journal of Environmental Health, (2009); 71(6): 61-66, ISSN No.: 0022-0892 IF-1.179
  55. Anjana Sharma, Susheel K Singh and Sunita Patra “Intra and interspecies variations among environmental Klebsiella isolates” Asian Journal of Experimental Sciences, (2007); 21(2); 435-443, ISSN No.: 0971-5444 IF-0.38

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