Dr. Manoranjan Ranjit

Scientist Profile

Dr. Manoranjan Ranjit


Date of Joining : 05/02/1986
Date of Joining(present post): 01/09/2019

Regional Medical Research Centre ,Indian Council of Medical Research Chandrasekharpur, Bhubaneswar-751023, ODISHA


Qr No C-1, RMRC Campus Chandrasekharpur, Bhubaneswar-751023,ODISHA

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Educational Qualifications:

M.Sc. (Zoology), Ph.D. (Zoology)

About Profile:

Research Experience
My research program investigates new diagnostic tools, pathogenesis and innate immunity in severe malaria and epidemiology of drug resistance for P falciparum. The other additional areas include epidemiology and control of rickettsial diseases like SrubTyphus, molecular epidemiology of Haemoglobinopaties & G6PD deficiency, intestinal parasitism and nutrition, molecular epidemiology and control of lymphatic Filariasis.
  1. National Academy of Vector Borne Diseases, Bhubaneswar
  2. Indian Society for Malaria and other Communicable Diseases, Delhi
  1. Kaeda JS, Chhotray GP, Ranjit MR, Bautista JM, Reddy PH, Stevens D, Naidu JM, Britt RP, Vulliamy TJ, Luzzato L and Mason PJ. A new Glucose 6 Phosphate dehydrogenase variant G6PD Orissa (44 Ala Gly), is the major polymorphic variant in tribal population in India. American Journal of Human Genetics 1995; 57: 1335-1341.
  2. Bhutani N, Ranjit MR, Yameen M, Singh N, Dev V, Pillai CR, Ansari MA and Sharma YD. Genetic diversity among field isolates of Plasmodium falciparum in India. Current Science 1998; 75(2): 160-163.
  3. Ranjit MR and Sharma YD. Genetic polymorphism of falciparum malaria vaccine candidate antigen genes among field isolates in India. American Journal of Tropical Medicine and Hygiene 1999; 61: 103-108.
  4. Chhotray GP, Ranjit MR and Mohapatra M. Occurrence of asymptomatic microscopic haematuria in a filarial endemic area of Orissa, India. Journal of Communicable Disease 2000; 32 (2): 85-93.
  5. Chhotray GP, Mohapatra M, Acharya AS and Ranjit MR. A clinico-epidemiological perspective of lymphatic filariasis in Satyabadi block of Puri district, Orissa. Indian Journal of Medical Research 2001; 114: 65-71.
  6. Chhotray GP, Dash BP, Ranjit MR, Cohla RB and Mohanty D. Haemoglobin E / Thalassaemia An experience in the eastern Indian state of Orissa. Acta Haematologica 2003; 109: 214-216.
  7. Chhotray GP, Dash BP and Ranjit MR. Spectrum of Haemoglobinopathies in Orissa, India. Haemoglobin 2004; 28: 117-122.
  8. Vathsala PG, Pramanik A, Dhanasekaran S, Usha Devi C, Pillai CR, SubbaRao SK, Ghosh SK, Tiwari SN, Sathyanarayan TS, Deshpande PR, Mishra GC, Ranjit MR, Dash AP, Rangarajan PN and Padmanaban G. Widespread occurrence of the Plasmodium falciparum Chloroquine resistance transporter (PfCRT) gene haplotypes SVMNT in P. falciparum malaria in India. American Journal of Tropical Medicine and Hygiene 2004; 70: 256-259.
  9. Ranjit MR, Das A, Chhotray GP, Dash BP and Das BN. The PfCRT (K76T) point mutation favours clone multiplicity in P. falciparum infection. Tropical Medicine and International Health 2004; 9: 857-861.
  10. Ranjit MR, Das A, Chhotray GP, Rath RN and Kar SK. The PfCRT (K76T) point mutation and its usefulness for monitoring chloroquine resistance. Annals of Tropical Medicine and Parasitology 2004; 98: 879-882.
  11. Ranjit MR, Das A, Das BP, Das BN, Dash BP and Chhotray GP. Distribution of Plasmodium falciparum genotypes in clinically mild and severe malaria cases in Orissa, India. Transactions of Royal Society of Tropical Medical and Hygiene 2005; 99: 389-395.
  12. Nishank SS, Ranjit MR, Kar SK, Chhotray GP Molecular variants of β thalassaemia traits and its clinical significance in Orissa Hematology. 2009, 14:1-7.
  13. Nishank SS, Chhotray GP, Kar SK, Ranjit MR Molecular variants of G6PD deficiency among certain tribal communities of Orissa, India. Annals of Human Biology 2008, 35:355-61.
  14. Nishank SS, Ranjit MR, Chhotray GP. First report of a nonsense mutation at codon 15(TGG-->TAG) in exon 1 of the beta globin gene in a beta thalassemia trait in State of Orissa, India. Hematology 2008, 13:65-67.
  15. Ranjit MR, Sahu U, Khatua CR, Mohapatra BN, Achraya AS and Kar SK. Chloroquine-resistant p falciparum parasites and severe malaria in Orissa . Current Science 2009, 96:1608-1611.
  16. Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit MR. Endothelial nitric oxide synthase (eNOS) gene polymorphisms and P falciparum infection in Indian adults. Infection and Immunity 2009, 77:2943-2947.
  17. Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit MR. The CCTTT pentanucleotide microsatellite in iNOS promoter influences the clinical outcome in P. falciparum infection. Parasitology Research 2009, 104:1315-1320
  18. Das A, Das TK, Sahu U, Das BP, Kar SK, Ranjit MR. CD36 T188G gene polymorphism and severe falciparum malaria in India. Transactions of the Royal Society of Tropical Medicine and Hygiene 2009, 103:687-690.
  19. Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit MR. Genetic variation in neuronal nitric oxide synthase (nNOS) gene and susceptibility to cerebral malaria in Indian adults. Infection Genetics and Evolution 2009, 9: 908-911.
  20. Rout R, Mohapatra BN, Kar SK, Ranjit MR. Genetic complexity and transmissibility of Plasmodium falciparum parasites causing severe malaria in central-east coast India. Tropical Biomedicine 2009, 26: 165-172.
  21. Dhangadamajhi, G, Kar, SK, Ranjit MR. High prevalence and gender bias in distribution of Plasmodium malariae infection in central east-coast India. Tropical Biomedicine 2009, 26: 326333.
  22. Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit MR A new allele (eNOS4e) in the intron 4 (VNTR) of eNOS gene in malaria infected individuals of the population of Orissa (an eastern Indian state) Nitric Oxide 2010, 22: 5859.
  23. Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit MR Gene polymorphisms in angiotensin I converting enzyme (ACE I/D) and angiotensin II converting enzyme (ACE2 C→T) protect against cerebral malaria in Indian adults. Infection Genetics and Evolution 10 (2010) 337341.
  24. Dhangadamajhi G, Kar SK, Ranjit MR. The survival strategies of Malaria Parasite in the Red Blood Cell and Host Cell Polymorphism. Malaria Research and Treatment 2010, 1-9.
  25. Rout R, Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit MR.Genetic diversity of PfEMP1-DBL1-α and its association with severe malaria in a hyperendemic state of India. Asian Pacific Journal of Tropical Medicine 2010, 412-420.
  26. Rout R, Dhangadamajhi G, Mohapatra BN, Kar SK, Ranjit MR. High CR1 level and related polymorphic variants are associated with cerebral malaria in eastern-India. Infection Genetics and Evolution 2011, 11:139-44.
  27. Dhangadamajhi G, Rout BK, Kar SK, Ranjit MR. Genetic diversity of Plasmodium vivax in a hyperendemic area predominated by Plasmodium falciparum; A preliminary study. Tropical Biomedicine 2010, 27:578-584.
  28. Das Sutar S, Gupta B, Ranjit MR, Kar SK and Das A. Sequence Analysis of Coding DNA fragments of Pfcrt and Pfmdr1 genes in Plasmodium falciparum isolates from Odisha, India. Mem Inst Oswaldo Cruz,Rio de Janeiro 2011,106:78-84.
  29. Mohapatra MK, Acharya SK and Ranjit MR TLR-2 I/D polymorphism protects from multiple complications in falciparum malaria J Infect Dis (Photon) 2013, 112: 215-221.
  30. Das Sutar SK, Dhangadamajhi G, Kar SK, Ranjit MR. Molecular monitoring of antimalarial drug resistance among Plasmodium falciparum field isolates from Odisha, India. Acta Tropica 2013, 126: 84-87.
  31. Patnaik M, Pati P, Swain SN, Mohapatra MK, Dwibedi B, Kar SK and Ranjit MR. Association of angiotensin-converting enzyme and angiotensin-converting enzyme-2 gene polymorphisms with essential hypertension in the population of Odisha, India. Ann Hum Biol 2014, 41(2):143-150.
  32. Bal MS, Sahu PK, Mandal N, Satapathy AK, Ranjit MR , Kar SK Maternal Infection Is a Risk Factor for Early Childhood Infection in Filariasis” PLOS NTD 2015, 30: DOI: 10.1371 /journal.pntd.0003955.
  33. Patnaik M, Pati P, Swain SN, Mohapatra MK, Dwibedi B, Kar SK and Ranjit MR. Gender specific association of Angiotensinogen gene polymorphisms with essential hypertension. IJFANS 2015, 4: 181-193.
  34. Dhangdamajhi G, Hazra RK, Ranjit MR Malaria in Odisha and future perspective J Infect Dis ( Photon) 2015, 114: 289-304.
  35. Bal MS, Ranjit MR, Achary KG, Satapathy AK. Maternal Filarial Infection Influences the Development of Regulatory T Cells in Children from Infancy to Early Childhood. PLOS NTD |DOI:10.1371/journal.pntd.0005144 November18, 2016.
  36. Pati P, Khuntia HK, Bal MS, Ranjit MR Optimization and Testing of LAMP assay for Diagnosis of Malaria, JPAM, 2016, 10(4): 3253-3256.
  37. Chhotray GP, Ranjit MR, Pal BB, Meher PK, Khuntia HK Incidence and Molecular Analysis of Vibrio cholerae among Some Primitive Tribes in Odisha, India Int J Curr Microbiol App Sci, 2017, 6(1): 51-61

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